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Published on: May 26, 2015
Duodenal Ulcer as a Postoperative Complication in the Donor in Living-Donor Liver Transplantation
M Kadohisa1, Y Sugawara1, K Shimata1
1Department of Transplantation and Pediatric Surgery, Kumamoto University, Kumamoto, Japan.
Introduction:
Donor safety is one of the most important factors in living-donor liver transplantation. Duodenal ulcer (DU) is a common postoperative complication. Here we aimed to reveal the risk factors associated with postoperative DU in the donors.
Methods:
Between April 2007 and March 2017, 318 cases underwent donor hepatectomy for liver transplantation at Kumamoto University Hospital. We classified the donors into two groups: a DU group and a non-DU group. DU was defined as mucosal break with unequivocal depth requiring an endoscopic procedure. The characteristics and clinical factors of the donors were retrospectively analyzed.
Results:
Postoperative DU occurred in 17 donors during the study period. The mean interval after donor hepatectomy to occurrence of DU was 124.8 ± 185.4 days. The two groups were comparable in terms of age at time of the donor hepatectomy (P = .45). The male-to-female ratio (P = .03) was significantly different between the two groups and left-side hepatectomy was performed more often in the DU group (P = .003). Multivariable logistic regression revealed that left-side hepatectomy was independently associated with postoperative DU in the donors.
Conclusions:
These findings indicated that left-side hepatectomy is a risk factor for postoperative DU in the donors.
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