Related Experiment Video
Updated: Feb 11, 2026

08:07
Author Spotlight: Advancing Labor Management Through Electromyometrial Imaging for Understanding Uterine Contractions
Published on: May 26, 2023
1.9K
No. 292-Abnormal Uterine Bleeding in Pre-Menopausal Women
Sukhbir Singh1, Carolyn Best2, Sheila Dunn2
1Ottawa, ON.
Summary
Abnormal uterine bleeding (AUB) affects many women, causing significant health burdens. This guideline offers evidence-based diagnosis and management strategies for healthcare providers to improve patient care and outcomes.
Area of Science:
- Gynecology
- Women's Health
- Evidence-Based Medicine
Background:
- Abnormal uterine bleeding (AUB) is a prevalent condition impacting women's quality of life and imposing a substantial healthcare burden.
- Approximately 30% of women seek medical help for AUB during their reproductive years.
Purpose of the Study:
- To establish current, evidence-based guidelines for diagnosing and managing abnormal uterine bleeding in reproductive-aged women.
- To provide healthcare professionals with tools for the latest evidence-based care.
Main Methods:
- A guideline committee with diverse expertise reviewed English medical literature and existing guidelines.
- Recommendations were developed through consensus statements and approved by the SOGC Executive and Council.
- Literature searches included MEDLINE and Cochrane Library from 1999-2013, encompassing systematic reviews, RCTs, and observational studies.
Main Results:
- The document summarizes current evidence on AUB diagnosis, investigations, and medical/surgical management.
- Recommendations are intended for adaptation by healthcare workers in clinical practice.
- Outcomes evaluated include AUB's impact on quality of life and intervention effectiveness.
Conclusions:
- Standardizing terminology, adopting a systematic diagnostic approach, and implementing stepwise interventions are crucial for managing AUB.
- The primary goal is to initiate treatment with medical modalities, progressing to minimally invasive surgery if needed.
- Effective management of abnormal uterine bleeding aims to achieve patient-satisfactory outcomes.
Keywords:
Menorrhagiaabnormal uterine bleedingendometrial ablationheavy menstrual bleedinghysterectomyMore Related Videos
Related Concept Videos
Menopause
5.0K
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
5.0K
Abnormal Proliferation
5.2K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
5.2K
Uterine Tubes
2.5K
The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
2.5K
Bleeding in Fresh Concrete
611
Bleeding in fresh concrete occurs when water from the mix rises to the surface. This happens because the mix's solid components fail to retain all the water as they settle, leading to separation where water collects at the top. The severity of bleeding can be measured by assessing the total settlement or by noting the decrease in height per unit height of concrete.
Bleeding can cause several issues in the concrete structure. Sometimes, the rising water gets trapped beneath large aggregate...
Bleeding can cause several issues in the concrete structure. Sometimes, the rising water gets trapped beneath large aggregate...
611
pre-mRNA Processing
57.6K
In eukaryotic cells, transcripts made by RNA polymerase are modified and processed before exiting the nucleus. Unprocessed RNA is called precursor mRNA or pre-mRNA to distinguish it from mature mRNA.
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a “cap” to the 5’ end of the growing transcript. In this process, a 5’ phosphate is replaced by modified guanosine that has a methyl group attached to it (7-Methyl...
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a “cap” to the 5’ end of the growing transcript. In this process, a 5’ phosphate is replaced by modified guanosine that has a methyl group attached to it (7-Methyl...
57.6K
Chromatin Structure Regulates pre-mRNA Processing
8.3K
In eukaryotic cells, nascent mRNA transcripts need to undergo many post-transcriptional modifications to reach the cell cytoplasm and translate into functional proteins. For a long time, transcription and pre-mRNA processing were considered two independent events that occur sequentially in the cell. However, it has now been well established that transcription and pre-mRNA processing are two simultaneous processes that are precisely regulated inside the cell.
The chromatin structure, especially...
The chromatin structure, especially...
8.3K

