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Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
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Calcific myonecrosis mimicking soft tissue sarcoma: A case report
Yuichiro Ukon1,2, Takaaki Tanaka1,2, Shigenori Nagata3
1Department of Orthopaedic Surgery, Belland General Hospital, Sakai, Osaka 599-8247, Japan.
Oncology Letters
|May 8, 2018
Summary
Calcific myonecrosis is a rare soft tissue condition. This report details two cases, highlighting fascial herniation on CT images, aiding differentiation from malignancies.
Area of Science:
- Orthopedics
- Radiology
- Pathology
Background:
- Calcific myonecrosis is a rare soft tissue condition with unclear pathophysiology.
- Previous reports suggest a link to compartment syndrome, necrosis, fibrosis, hemorrhage, and calcification, often post-trauma in lower legs.
Purpose of the Study:
- To report two cases of calcific myonecrosis following prolonged periods after lower leg trauma.
- To focus on imaging evidence of late local enlargement due to fascial herniation, a feature not previously emphasized.
Main Methods:
- Case report of two patients with calcific myonecrosis.
- Computed Tomography (CT) imaging analysis to evaluate disease characteristics and fascial involvement.
Main Results:
- CT images revealed disruption of the calcified fascia and extrafascial disease expansion in both cases.
- Observed late focal enlargement, consistent with herniation through the muscle fascia.
Conclusions:
- This is the first report to focus on imaging evidence of fascial herniation in calcific myonecrosis.
- Identifying fascial herniation may assist clinicians in differentiating calcific myonecrosis from soft tissue malignancies.
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