The top 50 cited articles on chordomas.

Area of Science:

• Oncology
• Orthopedic Surgery
• Medical Research Impact

Background:

• Chordomas are rare, malignant primary tumors originating from the spine.
• En-bloc resection in the mobile spine and sacrum is linked to reduced recurrence rates.
• Understanding influential research is key to advancing chordoma management.

Purpose of the Study:

• To identify and characterize the top-cited articles in chordoma research.
• To analyze trends and origins of highly impactful chordoma literature.
• To inform future research directions and clinical practice.

Main Methods:

• A comprehensive literature search was conducted using ISI Web of Science for the keyword 'chordoma' (1900-2017).
• Articles were ranked by citation count, with the top 50 selected for further analysis.
• Characteristics analyzed included publication details, origin, and paper topic.

Main Results:

• 1,043 articles met the search criteria; the top 50 were cited 65-290 times.
• Most influential articles were published between 1926-2012, predominantly from the United States (66%) and Italy (14%).
• Key journals included *Cancer* (9 articles) and *Journal of Bone and Joint Surgery* (4 articles); clinical papers constituted 44% of the top 50.

Conclusions:

• The most cited chordoma research predominantly features clinical papers.
• These influential articles frequently originate from the United States.
• Leading journals for high-impact chordoma research are *Cancer* and the *Journal of Bone and Joint Surgery*.