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Updated: Feb 11, 2026

Oleic Acid-Injection in Pigs As a Model for Acute Respiratory Distress Syndrome
Published on: October 26, 2018
At 50 years of the description of acute respiratory distress syndrome
Raúl Carrillo-Esper1, Gilberto Felipe Vázquez-De Anda2, Cynthia Ivonne Mejía-Pérez2
1Academia Nacional de Medicina de México. Ciudad de México, México.
Abstract:
In 1967, Ashbaugh et al. published in the Lancet the description of a new entity, for which they coined the name "adult respiratory distress syndrome". On that article, they thoroughly described 12 patients who had respiratory distress with bilateral pulmonary infiltrates and oxygen therapy-refractory hypoxemia. For its management, emphasis was made on the importance of intubation and mechanical ventilation with positive end-expiratory pressure. At 50 years of its first publication, great advances on the knowledge of this condition have been achieved, which has influenced on patient management and survival. To celebrate this 50th anniversary, the National Academy of Medicine of Mexico organized a symposium with the purpose to spread the knowledge about this condition, recognize the researchers who made the original description and those who over the course of 50 years of history have contributed to its better understanding. The symposium addressed the topics of lung-kidney interaction, molecular bases of the disease and therapeutic advances.
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