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Types of Fever01:25

Types of Fever

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Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
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Related Experiment Video

Updated: Feb 11, 2026

Building a Better Mosquito: Identifying the Genes Enabling Malaria and Dengue Fever Resistance in A. gambiae and A. aegypti Mosquitoes
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[Lujo hemorrhagic fever].

T E Sizikova1, V N Lebedev1, S I Syromyatnikova1

  • 148th Central Scientific Research Institute, Sergiev Posad, 141306, Russian Federation.

Voprosy Virusologii
|May 8, 2018
PubMed
Summary
This summary is machine-generated.

Lujo hemorrhagic fever (LHF) is a severe viral illness caused by Lujo virus (LUJV), presenting symptoms similar to Lassa hemorrhagic fever. This deadly disease, first identified in South Africa, highlights the urgent need for understanding and prevention strategies.

Keywords:
Lujo hemorrhagic feverLujo virus (LUJV)RNAarenavirusesmethods of diagnosticsphylogenetic analysisreservoir of infectionreviewviral hemorrhagic feverviral structural proteins

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Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • Lujo hemorrhagic fever (LHF) is a severe viral illness characterized by fever, headache, vomiting, diarrhea, and hemorrhagic syndrome.
  • LHF presents a clinical picture similar to Lassa hemorrhagic fever, another significant viral hemorrhagic fever.
  • The first documented outbreak occurred in Johannesburg, South Africa, in 2008, with significant mortality.

Purpose of the Study:

  • To review and consolidate data on the epidemiology, clinical characteristics, and diagnostics of Lujo hemorrhagic fever.
  • To discuss the properties of Lujo virus (LUJV), the causative agent, based on phylogenetic analysis.
  • To outline recommended precautions for preventing secondary transmission of LHF.

Main Methods:

  • Literature review and data synthesis on LHF cases and Lujo virus.
  • Phylogenetic analysis of Lujo virus to understand its properties and relationships.
  • Review of clinical case data and epidemiological information.

Main Results:

  • Lujo virus (LUJV), an arenavirus, is identified as the etiologic agent of LHF.
  • The 2008 outbreak in South Africa resulted in a high fatality rate, including secondary transmission to healthcare workers.
  • LHF shares clinical similarities with Lassa hemorrhagic fever, emphasizing its potential public health threat.

Conclusions:

  • Lujo hemorrhagic fever is a dangerous viral disease caused by Lujo virus, with a high mortality rate.
  • Understanding the epidemiology, clinical presentation, and transmission dynamics of LHF is crucial for effective management.
  • Strict adherence to preventive measures is essential to control the spread of LHF, particularly in healthcare settings.