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Neurobehavioural outcome in 6-18 year old children after trauma in pregnancy: Case-control study

B J van der Knoop1, K J Oostrom2, I A Zonnenberg3

  • 1Department of Obstetrics and Gynaecology, VU University Medical Center, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands; Neuroscience Campus, VU University, Amsterdam, The Netherlands.

European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society
|May 9, 2018
PubMed

Insights

Children exposed to maternal trauma during pregnancy showed similar long-term neurobehavioral development compared to controls. However, these children experienced more hospitalizations, with the cause remaining unclear.

Area of Science:

  • Obstetrics and Gynecology
  • Pediatric Neurology
  • Developmental Psychology

Background:

  • Maternal trauma affects approximately 7% of pregnancies.
  • The long-term developmental impact on children exposed to maternal trauma in utero is not well understood.

Purpose of the Study:

  • To assess the neurobehavioral outcomes of children aged 6-18 years born after maternal trauma during pregnancy.
  • To compare these outcomes with a matched control group of children born after uncomplicated pregnancies.

Main Methods:

  • A case-control study was conducted at a tertiary medical center.
  • Children born after maternal hospitalization for trauma (1995-2005) were compared to controls born during the same period.
  • Maternal trauma severity was assessed, and children's health, motor development, educational level, and behavior (using the Child Behavior Checklist) were evaluated via questionnaires.

Main Results:

  • Data from 34 cases and 28 controls were analyzed.
  • Maternal traumas primarily involved motor vehicle accidents and falls, with few severe injuries.
  • No significant differences were observed in health, motor development, educational level, or behavioral scores between groups.

Conclusions:

  • Children exposed to maternal trauma before birth, particularly non-severe cases, exhibit comparable long-term neurobehavioral development to unexposed peers.
  • A notable exception was a higher incidence of hospitalizations in the trauma-exposed group, without a clear explanation.
Abstract

Keywords:
Case–controlMaternal injuriesNeurobehavioural outcomeTrauma in pregnancy

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