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Updated: Feb 11, 2026
07:38
Carrier Lifetime Measurements in Semiconductors through the Microwave Photoconductivity Decay Method
Published on: April 18, 2019
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Germicidal Activity against Carbapenem/Colistin-Resistant Enterobacteriaceae Using a Quantitative Carrier Test Method
Hajime Kanamori1,2, William A Rutala3,2, Maria F Gergen3
1Department of Hospital Epidemiology, University of North Carolina Health Care, Chapel Hill, North Carolina, USA kanamori@med.tohoku.ac.jp.
Antimicrobial Agents and Chemotherapy
|May 9, 2018
Summary
Germicides commonly used in healthcare facilities are likely effective against carbapenem/colistin-resistant Enterobacteriaceae. This study used a disc-based quantitative carrier test to assess germicide efficacy against these difficult-to-treat pathogens.
Area of Science:
- Antimicrobial resistance
- Infection control
- Public health microbiology
Background:
- Carbapenem-resistant Enterobacteriaceae (CRE) and colistin-resistant Enterobacteriaceae (CrE) pose significant treatment challenges.
- Limited data exists on the susceptibility of these multidrug-resistant organisms to common germicides.
Purpose of the Study:
- To evaluate the efficacy of various germicides against carbapenem/colistin-resistant Enterobacteriaceae.
- To determine if standard healthcare germicides can effectively eliminate these emerging pathogens.
Main Methods:
- Utilized a disc-based quantitative carrier test method.
- Simulated real-world healthcare surface contamination scenarios.
- Assessed germicide effectiveness against carbapenem/colistin-resistant Enterobacteriaceae isolates.
Main Results:
- Germicides commonly employed in healthcare settings demonstrated efficacy against carbapenem/colistin-resistant Enterobacteriaceae.
- The disc-based quantitative carrier test provided relevant data comparable to clinical settings.
Conclusions:
- Appropriate use of standard healthcare germicides is likely effective in controlling carbapenem/colistin-resistant Enterobacteriaceae.
- This finding supports current infection control practices for managing multidrug-resistant organisms.
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