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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Aging01:26

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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Behavioral Assessment of the Aging Mouse Vestibular System
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Assessing the Effectiveness of the Aging Mastery Program.

Lisa Ferretti1, Philip McCallion2, Emily McDonald3

  • 1School of Social Work, Temple University, Philadelphia, PA 19122, USA. lisa.ferretti@temple.edu.

Healthcare (Basel, Switzerland)
|May 9, 2018
PubMed
Summary

The Aging Mastery Program (AMP) effectively improved physical activity and advanced care planning in older adults. This evidence-based intervention supports successful aging through active self-management strategies.

Keywords:
advanced planningagingevidence-basedphysical activity

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Area of Science:

  • Gerontology
  • Public Health
  • Health Psychology

Background:

  • Successful aging hinges on active self-management and personal control over one's life trajectory.
  • While some older adults proactively manage aging, others require structured support through evidence-based programs.
  • The Aging Mastery Program (AMP) was created to address these needs by empowering seniors.

Purpose of the Study:

  • To evaluate the effectiveness of the Aging Mastery Program (AMP) as an evidence-based intervention for older adults.
  • To assess AMP's impact on general health, quality of life, patient activation, physical activity, and advanced care planning.
  • To determine if AMP facilitates successful aging through enhanced self-determination and active management.

Main Methods:

  • A crossover design was employed to test the AMP intervention.
  • The study involved ten senior centers and aging network agencies.
  • Key outcome measures included general health, quality of life, patient activation, physical activity, and advanced care planning.

Main Results:

  • A statistically significant improvement was observed in physical activity levels among participants (p < 0.05).
  • Significant enhancements were also noted in advanced care planning (p < 0.05).
  • The program demonstrated positive impacts on specific domains relevant to successful aging.

Conclusions:

  • The findings support the Aging Mastery Program's (AMP) effectiveness as a valuable intervention for older adults.
  • AMP serves as a robust, evidence-based tool for programming aimed at promoting successful aging.
  • The program's success in improving physical activity and advanced care planning highlights its utility in empowering seniors.