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Related Experiment Video

Updated: Feb 10, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Mix headache: A valid clinical entity?

Tapas Kumar Aich1, Uttam Gupta2, Sandip Subedi2

  • 1Department of Psychiatry, Baba Raghav Das Medical College, Gorakhpur, Uttar Pradesh, India.

Indian Journal of Psychiatry
|May 9, 2018
PubMed
Summary
This summary is machine-generated.

Chronic daily headache patients often benefit from a combination of anti-migraine and anti-stress treatments. This study validates a "mix headache" subtype, improving treatment strategies for chronic daily headache.

Keywords:
Chronic daily headachechronic migrainechronic tension-type headache“mix headache”

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Area of Science:

  • Neurology
  • Psychiatry

Background:

  • Chronic daily headache (CDH) is a prevalent condition.
  • Current treatment approaches often combine anti-migraine and anti-stress medications.
  • The clinical diagnosis of CDH can be complex, encompassing both chronic migraine (CM) and chronic tension-type headache (CTTH).

Purpose of the Study:

  • To investigate the validity of a
  • To explore the prevalence of psychiatric comorbidities in CDH patients.
  • To propose a
  • CDH - mix headache
  • subtype based on clinical presentation and comorbidities.

Main Methods:

  • A cohort of 70 primary CDH patients (aged 15-55) was studied.
  • Patients were classified as CM or CTTH based on symptom profiles adhering to International Headache Society guidelines.
  • Schedules for Clinical Assessment in Neuropsychiatry (SCAN) and ICD-10 criteria were used to assess psychiatric comorbidities.

Main Results:

  • 68.6% of patients were diagnosed with CM, and 31.4% with CTTH.
  • A significant comorbidity of anxiety and depressive illness was found in 67.2% of patients (47 individuals).
  • Of those with comorbidities, 34 were in the CM group and 13 in the CTTH group.

Conclusions:

  • The study supports the existence of a distinct
  • CDH - mix headache
  • subtype, comprising 67.2% of the studied population.
  • This subtype designation aids in understanding treatment responses to combined anti-migraine and anti-stress medications.
  • Further research can refine diagnostic criteria and therapeutic strategies for CDH subtypes.