Related Experiment Video
Updated: Feb 10, 2026
08:02
Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
Published on: October 25, 2024
855
Chronic Pulmonary Silicone Embolism from Breast Augmentation Is Not a Common Finding in Explanted Lungs
Jarmanjeet Singh1, Hanine Inaty2, Sanjay Mukhopadhyay3
1Internal Medicine Residency Program, The Cleveland Clinic Foundation, Cleveland, OH, USA.
Pulmonary Medicine
|May 9, 2018
Summary
This study found no evidence of chronic pulmonary silicone embolism in female lung transplant recipients with breast augmentation. Breast augmentation does not appear to significantly contribute to lung diseases requiring transplantation.
Area of Science:
- Pulmonary Medicine
- Pathology
- Transplantation Surgery
Background:
- Acute pulmonary silicone embolism (APSE) from injections is known.
- Chronic pulmonary silicone embolism (CPSE) from breast implants is rarely reported.
- Prevalence of CPSE in breast augmentation patients is unknown.
Purpose of the Study:
- Determine CPSE prevalence in female lung transplant recipients with breast augmentation.
- Investigate breast augmentation's role in chronic lung diseases requiring lung transplantation.
Main Methods:
- Retrospective chart review of female lung transplant recipients with prior breast augmentation.
- Pathologic reexamination of explanted lungs for CPSE by an expert pathologist.
Main Results:
- 10 of 578 (1.73%) female lung transplant recipients had breast augmentation.
- No pathologic evidence of CPSE found in explanted lungs of these 10 patients.
- 84 slides examined from 10 cases showed no signs of chronic silicone embolism.
Conclusions:
- CPSE is not associated with lung diseases leading to transplantation.
- Breast augmentation is not a significant factor in pulmonary disease requiring lung transplantation.
- Further research needed on CPSE prevalence and breast augmentation's pulmonary impact.
Related Concept Videos
01:29Pulmonary Embolism I: Introduction
761
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
761
01:27Pulmonary Embolism III: Nursing Management
454
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
454
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
476
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
476
01:24Chronic Obstructive Pulmonary Disease
2.6K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.6K
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
3.9K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
3.9K
01:29Chronic Obstructive Pulmonary Disease-V: Management
3.2K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Smoking Cessation
3.2K