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High-Content Imaging Phenotypic Screen for Neurogenesis Using Primary Neural Progenitor Cells

Li Sharon Wu1, Jingjun Li2

  • 1School of Life Sciences, Nanchang University, Nanchang, China.

Methods in Molecular Biology (Clifton, N.J.)
|May 9, 2018
PubMed
Summary

Researchers discovered small molecules that promote neurogenesis, the creation of new neurons from neural progenitor cells (NPCs). This study outlines methods for identifying these compounds and understanding the pathways involved in neuronal development.

Keywords:
High-content imagingNeural progenitor cellsNeurogenesisNeuronal differentiationPhenotypic screenSmall-molecule chemical library

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