Related Experiment Video
Updated: Feb 10, 2026
09:04
DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
Published on: February 27, 2014
49.0K
Post-operative complications in elderly onset inflammatory bowel disease: a population-based study
S-C Sacleux1, H Sarter2,3, M Fumery4
1Epimad Registry, Hôpital Charles Nicolle, Rouen University Hospital, Rouen, France.
Alimentary Pharmacology & Therapeutics
|May 9, 2018
Summary
Elderly patients with inflammatory bowel disease (IBD) face significant post-operative complications, with nearly one-third experiencing adverse events. Emergency surgery is a primary risk factor for these complications in older adults.
Area of Science:
- Gastroenterology
- Surgical Outcomes
- Geriatric Medicine
Background:
- Incidence of Inflammatory Bowel Disease (IBD) diagnosed in individuals over 60 is rising.
- Limited data exists on post-operative complications in elderly-onset IBD patients.
Purpose of the Study:
- To determine the incidence of post-operative complications in elderly-onset IBD.
- To identify factors associated with these complications in patients over 60.
Main Methods:
- Analysis of the EPIMAD Cohort (1988-2006) including 841 incident IBD patients.
- Focus on 139 patients (17%) who underwent intestinal surgery (100 Crohn's disease, 39 ulcerative colitis).
- Median follow-up of 6 years, assessing early (<30 days) and long-term (≥30 days) complications.
Main Results:
- 36% of elderly IBD surgery patients experienced at least one complication.
- Early complications occurred in 17% of patients, with 59% being severe and infectious.
- Multivariate analysis identified acute severe colitis and emergency surgery as predictors of early complications.
- Female gender and delayed surgery (>3 months) were linked to long-term adverse effects.
Conclusions:
- Approximately one-third of elderly IBD patients undergoing surgery experience post-operative complications.
- Severe, infectious early complications are common, with emergency surgery being a major risk factor.
- Identifying risk factors is crucial for managing surgical outcomes in elderly IBD patients.
More Related Videos
Related Concept Videos
01:30Inflammatory Bowel Disease II: Crohn's Disease
1.2K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.2K
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
1.1K
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
1.1K
01:21Inflammatory Bowel Disease V: Surgical Management
630
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
630
01:29Inflammatory Bowel Disease IV: Pharmacological Management
718
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Pharmacologic...
718
01:30Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
840
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
840
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
3.9K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
3.9K