Related Experiment Video
Updated: Feb 10, 2026

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
Copper(I)-Catalyzed Three-Component Click/Persulfuration Cascade: Regioselective Synthesis of Triazole Disulfides
Weiguo Wang1, Yunzhi Lin1, Yudao Ma1
1Key Lab for Colloid and Interface Chemistry of Education Ministry, School of Chemistry and Chemical Engineering , Shandong University , Jinan 250100 , People's Republic of China.
Abstract:
A copper(I)-catalyzed three-component CuAAC/persulfuration reaction providing rapid access to asymmetric triazole disulfides has been developed. The interrupted click reaction shows broad substrate scope, complete regioselectivity, and excellent functional group tolerability.
Related Concept Videos
Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration
Intracellular Signaling Cascades
Rab Cascades
Regioselectivity of Electrophilic Additions-Peroxide Effect
Ribosomal RNA Synthesis
Ribosome biogenesis begins with the synthesis of 5S and 45S pre-rRNAs by distinct RNA polymerases. The primary transcripts are extensively processed and modified before they are bound and folded by ribosomal proteins and assembly factors,...
Transfer RNA Synthesis
Each of these chemical modifications is carried by a specific enzyme, post-transcription. All of these enzymes have unique base and site-specificity. Methylation, the most common chemical modification, is carried by at least nine different enzymes, with...

