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[Implication of lipid peroxidation in triethyltin poisoning in the rat]
R Boulieu1, J F Munoz, O Macovschi
1Laboratoire de Chimie biologique, Institut national des Sciences appliquées, Villeurbanne.
Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales
|January 1, 1988
Abstract:
Triethyltin intoxication induces, in vivo, a significant increase of malondialdehyde concentration in rat brain. After treatment with a Ginkgo biloba extract, an extract known to possess antiedematous and radical scavenging properties, the malondialdehyde level in the brain is significantly decreased. This suggests that a lipid peroxidation process is associated with cerebral oedema induced by triethyltin.