A novel approach to automatically quantify the level of coincident activity between EMG and MMG signals

Although previous studies have highlighted both similarities and differences between the timing of electromyography (EMG) and mechanomyography (MMG) activities of muscles, there is no method to systematically quantify the temporal alignment between corresponding EMG and MMG signals. We proposed a novel method to determine the level of coincident activity in quasi-periodic MMG and EMG signals. The method optimizes 3 muscle-specific parameters: amplitude threshold, window size and minimum percent of EMG and MMG overlap using a particle swarm optimization algorithm to maximize the agreement (balanced accuracy) between electrical and mechanical muscle activity. The method was applied to bilaterally recorded EMG and MMG signals from 4 lower limb muscles per side of 25 pediatric participants during self-paced gait. Mean balanced accuracy exceeded 75% for all muscles except the lateral gastrocnemius, where EMG and MMG misalignment was notable (56% balanced accuracy). The proposed method can be applied to the criterion-driven comparison of simultaneously recorded myographic signals from two different measurement modalities during a motor task.