Related Experiment Video
Updated: Feb 10, 2026

Evaluation of the Efficacy of the H. pylori Protein HP-NAP as a Therapeutic Tool for Treatment of Bladder Cancer in an Orthotopic Murine Model
Published on: May 29, 2015
Enhancing the Therapeutic Efficacy of Cancer Treatment With Cannabinoids
Sayeda Yasmin-Karim1,2,3, Michele Moreau2,3,4, Romy Mueller1,2,5
1Radiation Oncology, Brigham and Women's Hospital, Boston, MA, United States.
Abstract:
Over the years, many in vitro and in vivo studies have shown the antineoplastic effects of cannabinoids (CBDs), with reports advocating for investigations of combination therapy approaches that could better leverage these effects in clinical translation. This study explores the potential of combination approaches employing CBDs with radiotherapy (RT) or smart biomaterials toward enhancing therapeutic efficacy during treatment of pancreatic and lung cancers. In in vitro studies, clonogenic assay results showed greater effective tumor cell killing, when combining CBDs and RT. Meanwhile, in vivo study results revealed major increase in survival when employing smart biomaterials for sustained delivery of CBDs to tumor cells. The significance of these findings, considerations for further research, and viable roadmap to clinical translation are discussed.
More Related Videos
Related Concept Videos
Treatment Resistant Cancers
Self-Efficacy
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Two synthetic agonists of THC,...
Therapeutic Index
Self-Evaluation: Self-Enhancement and Self-Verification

