A comparison of ventricular systolic function indices provided by VolumeView/EV1000™ and left ventricular ejection

Nitchakan Nakwan1, Ply Chichareon2, Bodin Khwannimit3,4

  • 1Division of Critical Care Medicine, Department of Internal Medicine, Prince of Songkla University, Hat Yai, Songkhla, 90110, Thailand.

Insights

Cardiac Function Index (CFI) and Global Ejection Fraction (GEF) measured by VolumeView/EV1000™ reliably estimate Left Ventricular Ejection Fraction (LVEF) in septic shock patients. These indices show strong correlation and predictive ability for assessing LV systolic function.

Area of Science:

  • Critical Care Medicine
  • Cardiology
  • Hemodynamics

Background:

  • Septic shock poses significant challenges in assessing cardiac function.
  • Accurate monitoring of left ventricular systolic function is crucial for patient management.
  • Echocardiography is a standard but sometimes limited method for evaluating ejection fraction.

Purpose of the Study:

  • To compare Cardiac Function Index (CFI) and Global Ejection Fraction (GEF) from VolumeView/EV1000™ with Left Ventricular Ejection Fraction (LVEF) by echocardiography.
  • To evaluate the correlation between CFI, GEF, and LVEF in septic shock patients.
  • To assess the predictive ability of CFI and GEF for different LVEF thresholds.

Main Methods:

  • Prospective observational study in a medical intensive care unit.
  • Inclusion of 32 mechanically ventilated septic shock patients.
  • Simultaneous measurement of CFI, GEF (VolumeView/EV1000™), and LVEF (echocardiography).

Main Results:

  • Strong correlation found between CFI and GEF (r=0.82, P<0.0001).
  • Significant correlations observed between CFI and LVEF (r=0.56, P<0.0001) and GEF and LVEF (r=0.71, P<0.0001).
  • CFI and GEF demonstrated good predictive ability for LVEF thresholds (AUC 0.875-0.934).

Conclusions:

  • CFI and GEF obtained by VolumeView/EV1000™ correlate well with LVEF.
  • These indices provide a reliable estimation of left ventricular systolic function in septic shock.
  • CFI and GEF are valuable tools for monitoring cardiac function in critically ill patients.

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