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[Pregnancy: a way of recovering from prolactin-secreting adenoma? 18 cases]
C Bricaire1, V Kerlan, F Kuttenn
1Service d'Endocrinologie et Médecine de la reproduction, Hôpital Necker, Paris.
Abstract:
Fifteen patients with prolactin-secreting pituitary adenoma completed a total of 18 pregnancies. Changes in blood prolactin levels and computerized tomographic images of the pituitary gland were studied. No increase in size of the adenoma was observed, and in 2 cases the tumour was found to be necrotic in the post-partum period. In all patients the prolactinaemia significantly decreased immediately after delivery. Thus, by inducing partial necrosis of the adenoma pregnancy may result in post-partum reduction of blood prolactin levels.