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Effect of backpack carrying on forced vital capacity in cystic fibrosis: A randomized crossover-controlled trial

Yann Combret1,2,3, Clement Medrinal2,4,5, Guillaume Prieur2

  • 1Institut de Recherche Expérimentale et Clinique (IREC), Pôle de Pneumologie, ORL & Dermatologie, Université Catholique de Louvain, Brussels, Belgium.

Plos One
|May 10, 2018
PubMed

Insights

Unilateral backpack use significantly reduces lung function in children with cystic fibrosis (CF). This carrying method also demands greater cardio-respiratory effort in CF patients compared to healthy children.

Area of Science:

  • Pediatric Pulmonology
  • Biomechanics
  • Exercise Physiology

Background:

  • Backpack carrying is known to affect lung function in healthy children.
  • The impact of backpack use on lung function in children with cystic fibrosis (CF) remains uninvestigated.

Purpose of the Study:

  • To investigate the effects of different backpack carrying positions on lung function in children with CF.
  • To compare the cardio-respiratory responses to backpack carrying between children with CF and healthy peers.

Main Methods:

  • Three backpack conditions were assessed: no backpack (NB), bilateral backpack (BB), and unilateral backpack (UB) at 12.5% body weight.
  • Lung function (FVC, FEV1, MIP, MEP) and cardio-respiratory variables (VO2, VCO2, minute ventilation) were measured at rest and during a 10-minute walk.
  • Nine children with CF and 18 healthy children participated in the study.

Main Results:

  • Unilateral backpack (UB) carrying significantly reduced forced vital capacity (FVC) in children with CF compared to no backpack (NB).
  • Forced expiratory volume in 1 second (FEV1), maximal inspiratory pressure (MIP), and maximal expiratory pressure (MEP) showed greater decreases with UB in the CF group.
  • Children with CF exhibited larger increases in oxygen consumption (VO2), carbon dioxide production (VCO2), and minute ventilation during walking with a UB compared to healthy children.

Conclusions:

  • Unilateral backpack use negatively impacts lung function, specifically FVC, in children with cystic fibrosis.
  • Backpack carrying, particularly unilaterally, necessitates greater cardio-respiratory adjustments in children with CF relative to their healthy counterparts.
  • These findings highlight the importance of considering backpack carrying habits in the management of pediatric CF patients.
Abstract

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