Related Experiment Video
Updated: Feb 10, 2026

08:47
Spectral Confocal Imaging of Fluorescently tagged Nicotinic Receptors in Knock-in Mice with Chronic Nicotine Administration
Published on: February 10, 2012
14.0K
Symptomatic bradycardia due to nicotine intoxication.
Jin Hui Paik1, Soo Kang1, Areum Durey1
1Department of Emergency Medicine, Inha University School of Medicine, Incheon, Republic of Korea.
Revista Brasileira De Terapia Intensiva
|May 10, 2018
Summary
High-concentration liquid nicotine ingestion from e-cigarettes can cause severe poisoning. Prompt treatment with atropine and vasopressors is crucial for patient recovery from nicotine toxicity.
Area of Science:
- Toxicology
- Emergency Medicine
- Public Health
Background:
- Nicotine, a toxic alkaloid from tobacco, poses significant health risks, including respiratory and cardiac arrest.
- The rise of electronic cigarettes (e-cigarettes) has increased the risk of accidental liquid nicotine exposure due to direct handling.
Observation:
- A case of a patient who orally ingested a high concentration of liquid nicotine from e-cigarette liquid is presented.
- The patient exhibited bradycardia, hypotension (indicating parasympathetic stimulation), and impaired consciousness.
Findings:
- The patient's symptoms were consistent with acute nicotine poisoning.
- Successful management involved the administration of atropine and a vasopressor.
Implications:
- This case highlights the critical need for awareness regarding the dangers of liquid nicotine in e-cigarettes.
- Healthcare providers should be prepared to manage severe nicotine toxicity cases.
- Public health strategies are needed to mitigate risks associated with e-cigarette liquid handling.
More Related Videos
Related Concept Videos
Cholinergic Receptors: Nicotinic
5.8K
Nicotinic receptors are ligand-gated ion channels that are activated by acetylcholine and nicotine. Upon activation, they cause a rapid increase in the permeability of cells to K+, Na+, and Ca2+, followed by depolarization and excitation. They are in the autonomic ganglia, skeletal neuromuscular junction, CNS, and adrenal medulla.
There are two types of nicotinic receptors: neuromuscular (NM/NM/N1) and neuronal (NN/NN/N2). The two families differ based on their location and selectivity to...
There are two types of nicotinic receptors: neuromuscular (NM/NM/N1) and neuronal (NN/NN/N2). The two families differ based on their location and selectivity to...
5.8K
CNS Depressants: Alcohol and Nicotine
1.3K
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
1.3K

