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Updated: Feb 10, 2026

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri
Published on: September 12, 2025
Total Laparoscopic Hysterectomy Under Regional Anesthesia
Nash S Moawad1, Estefania Santamaria Flores, Linda Le-Wendling
1Section of Minimally-Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, and the Division of Acute and Perioperative Pain Medicine, Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida; the Department of Obstetrics and Gynecology, University of Massachusetts Medical School, Worcester, Massachusetts; and the Department of Chemistry, University of Florida, Gainesville, Florida.
This study details a successful total laparoscopic hysterectomy performed under epidural anesthesia, allowing the patient to remain awake. This approach offers potential benefits for select patients undergoing minimally invasive gynecologic surgery.
Area of Science:
- Gynecologic surgery
- Anesthesiology
- Minimally invasive procedures
Background:
- Laparoscopic hysterectomies are common in the US.
- Traditionally performed under general anesthesia.
- Regional anesthesia offers patient benefits but is less common for this procedure.
Observation:
- A 51-year-old woman underwent total laparoscopic hysterectomy, bilateral salpingectomy, and endometriosis excision.
- The procedure was performed using epidural anesthesia without sedation or narcotics.
- Adequate visualization was achieved with 12 mm Hg pneumoperitoneum and 15° Trendelenburg.
- Midthoracic and low lumbar epidural catheters were used, with bilevel positive airway pressure for respiratory support.
Findings:
- Total laparoscopic hysterectomy was successfully completed under epidural anesthesia with the patient fully awake.
- The procedure was uncomplicated.
Implications:
- Regional anesthesia, specifically epidural anesthesia, is a viable option for select patients undergoing laparoscopic hysterectomy.
- Careful patient selection, meticulous planning, and awareness of potential complications are crucial for success.
- This case highlights a potential alternative to general anesthesia for minimally invasive hysterectomy, offering enhanced recovery possibilities.
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