Rare ectopic metastasis from clear cell renal cell carcinoma to the chest wall after 10 years: A case report
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Updated: Feb 10, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
Published on: April 29, 2014
Chunyang Jiang1, Shan Zhao, Bingjun Yang
1Department of Thoracic Surgery, Tianjin Union Medical Center, Hongqiao District, Tianjin Department of Medical Oncology, The Second Hospital of Hebei Medical University, Xinhua District, Shijiazhuang Department of Pathology Department of Urology Surgery, Tianjin Union Medical Center, Hongqiao District, Tianjin Department of Nephrology, Hongqi Hospital, Mudanjiang Medical College, Aimin District, Mudanjiang, Heilongjiang, People's Republic of China.
Rationale:
Clear cell renal cell carcinoma (CCRCC) is an aggressive tumor associated with a high risk of metastasis and very low survival rate. In addition, it can cause extensive blood metastasis to the lungs, bones, and other organs. Chest wall metastatic tumors from primary CCRCC are rare.
Patient Concerns:
In this report, we present a case of metastatic chest wall tumor that originated from a CCRCC.
Diagnoses:
An 86-year-old man was diagnosed with chest wall tumor using chest computed tomography. After collecting tissues from the chest wall tumor via needle biopsy, the pathological examination was combined with positive immunoreaction of CD10, epithelial membrane antigen, and vimentin, and the patient was diagnosed with metastatic CCRCC in the chest wall deposits.
Interventions:
The patient received radiotherapy at 2.0 Gy per time for 25 times.
Outcomes:
Following 2 months of treatment, the chest wall tumor had shrunk by about one-third of its size.
Lessons:
Our patient developed a metastatic chest wall tumor that originated from a CCRCC for which right nephrectomy had been performed 10 years previously. Although as per the literature, chest wall metastasis from CCRCC is very rare, it is important to consider tumor metastasis after several years of treatment for precise diagnosis and proper treatment.
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