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The Role of Cardiokines in Heart Diseases: Beneficial or Detrimental?

Ye-Shun Wu1, Bin Zhu2, Ai-Lin Luo3

  • 1Department of Cardiology, The Third Affiliated Hospital of Soochow University, Changzhou 213003, China.

Biomed Research International
|May 11, 2018
PubMed

Insights

Cardiovascular disease is a major global health issue. This review explores cardiokines, heart-secreted proteins, as potential therapeutic targets for heart conditions.

Area of Science:

  • Cardiology
  • Molecular Biology
  • Biochemistry

Background:

  • Cardiovascular diseases (CVDs) are the primary cause of death globally.
  • There is a critical need for novel therapeutic strategies targeting CVDs.
  • Emerging research highlights the heart's role as an endocrine organ.

Purpose of the Study:

  • To review the role of cardiokines in cardiovascular disease pathogenesis.
  • To discuss the potential of cardiokines as therapeutic targets for heart diseases.

Main Methods:

  • Literature review of studies on cardiokines and heart disease.
  • Analysis of the physiological roles of specific cardiokines.
  • Evaluation of cardiokines as potential therapeutic agents.

Main Results:

  • Cardiokines are proteins secreted by the heart.
  • These proteins are crucial for maintaining heart homeostasis and responding to injury.
  • Dysregulation of cardiokines is implicated in the development of heart diseases.

Conclusions:

  • Cardiokines represent a promising area for therapeutic intervention in cardiovascular diseases.
  • Targeting specific cardiokines may offer novel treatment strategies for heart conditions.

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