Related Experiment Video
Updated: Feb 10, 2026

A Two-Step Method for Percutaneous Transhepatic Choledochoscopic Lithotomy
Published on: September 13, 2022
Comparable efficacy of endoscopic transpapillary gallbladder drainage and percutaneous transhepatic gallbladder
Chikara Iino1,2,3, Tadashi Shimoyama3, Takasato Igarashi2,3
1Department of Gastroenterology and Hematology, Hirosaki National Hospital, Aomori, Japan.
Insights
Endoscopic transpapillary gallbladder drainage (ETGBD) is effective for acute cholecystitis, offering similar outcomes to percutaneous transhepatic gallbladder drainage (PTGBD) but with a shorter hospital stay. ETGBD is a viable alternative treatment option.
Area of Science:
- Gastroenterology
- Interventional Endoscopy
- Surgical Outcomes
Background:
- Acute cholecystitis requires effective gallbladder drainage.
- Endoscopic transpapillary gallbladder drainage (ETGBD) is a known treatment.
- Comparison with percutaneous transhepatic gallbladder drainage (PTGBD) is limited.
Purpose of the Study:
- To compare the efficacy and safety of ETGBD versus PTGBD.
- To evaluate clinical outcomes and hospitalization duration.
- To identify factors predicting shorter hospital stays.
Main Methods:
- Retrospective study of 75 patients with acute cholecystitis requiring drainage.
- Propensity score matching analysis to compare ETGBD and PTGBD groups.
- Multivariate analysis to determine predictors of hospitalization period.
Main Results:
- Successful drainage rates were 77% for ETGBD and 100% for PTGBD.
- No significant differences in inflammatory markers between groups.
- ETGBD group had a significantly shorter hospitalization period.
- No significant difference in complication rates.
Conclusions:
- ETGBD is as effective as PTGBD for acute cholecystitis.
- ETGBD is associated with reduced hospitalization duration.
- ETGBD presents a valuable alternative treatment option.
Background And Study Aims:
Although endoscopic transpapillary gallbladder drainage (ETGBD) is reportedly useful in patients who have acute cholecystitis, its efficacy has not been compared to that of percutaneous transhepatic gallbladder drainage (PTGBD). We retrospectively compared the efficacy and safety of ETGBD and PTGBD in patients with acute cholecystitis.
Patients And Methods:
We studied 75 patients who required gallbladder drainage for acute cholecystitis between January 2014 and December 2016. Using propensity score matching analysis, we compared the clinical efficacy and length of hospitalization in patients successfully treated with ETGBD and PTGBD. Moreover, we assessed the predictive factors for hospitalization period < 30 days using multivariate analysis.
Results:
ETGBD and PTGBD were successfully performed in 33 patients (77 %) and 42 patients (100 %) ( P < 0.001). Twenty-seven matched pairs were obtained after propensity score matching analysis. No significant differences were observed between patients treated with ETGBD and those treated with PTGBD with respect to improvement in white blood cell count and serum C-reactive protein level. The length of hospitalization in patients treated with ETGBD was significantly shorter than in those treated with PTGBD regardless of the need for surgery. Multivariate logistic regression analysis revealed ETGBD (odds ratio, 7.07; 95 % confidence interval 2.22 - 22.46) and surgery (odds ratio 0.26; 95 % confidence interval 0.09 - 0.79) as independent factors associated with hospitalization period. There were no significant differences in occurrence of complications in ETGBD and PTGBD procedure.
Conclusions:
ETGBD was shown to be as useful as PTGBD for treatment of acute cholecystitis and was associated with shorter hospitalization period. ETGBD can be an alternative treatment option for acute cholecystitis at times when PTGBD is not possible.
More Related Videos
Related Concept Videos
Gallbladder
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cavity Drainage and Flashings in Masonry walls
Weep holes, strategically placed at the base of the cavity, are critical for draining accumulated water. These openings are created by leaving head...
Self-Efficacy
Comparing Copy Number Variations and SNPs
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
Endoscopic Studies II: Thoracocentesis
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...

