Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Genetic Engineering?00:49

What is Genetic Engineering?

80.4K
Overview
80.4K
Heat Engines01:10

Heat Engines

3.7K
A heat engine is a device used to extract heat from a source and then convert it into mechanical work used for various applications. For example, a steam engine on an old-style train can produce the work needed for driving the train.
Whenever we consider heat engines (and associated devices such as refrigerators and heat pumps), we do not use the standard sign convention for heat and work. For convenience, we assume that the symbols Qh, Qc, and W represent only the amounts of heat transferred...
3.7K
Internal Combustion Engine01:20

Internal Combustion Engine

2.8K
The internal combustion engine is a heat engine that uses the byproducts of combustion as the working fluid instead of using a heat transfer medium to transfer heat. The combustion is done in a way that produces high-pressure combustion products that can be expanded through a turbine or piston to create work. Internal combustion engines can again be categorized into three kinds: (1) spark ignition gasoline engines, most commonly used in automobiles, (2) compression ignition diesel engines that...
2.8K
Physiological Pharmacokinetic Models: Incorporating Hepatic Transporter-Mediated Clearance01:07

Physiological Pharmacokinetic Models: Incorporating Hepatic Transporter-Mediated Clearance

301
Drug transporters are critical in drug absorption, distribution, and excretion processes. They should be included in physiological-based pharmacokinetic (PBPK) models, which help predict human drug disposition. However, predicting this is challenging during drug development, especially when liver transport is involved. However, with a realistic representation of body transport processes, an accurate model may be possible.
A recent model describes pravastatin's hepatobiliary excretion,...
301
Applications of Logarithms01:28

Applications of Logarithms

278
Logarithmic functions are powerful tools for simplifying the mathematical representation of phenomena involving exponential changes. Their ability to convert multiplicative relationships into additive ones is especially valuable in various scientific and engineering contexts. One notable application of logarithms is measuring sound intensity, specifically through the decibel (dB) scale used in acoustics.Sound intensity levels vary over an extensive range, from the faintest audible whisper to...
278
Photoluminescence: Applications01:14

Photoluminescence: Applications

1.1K
Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Zinc-Releasing Fibrous Scaffolds Modulate Fibroblast, Endothelial, and Macrophage Interactions for Vascularized Tissue Engineering.

ACS applied materials & interfaces·2026
Same author

Zinc-integrated PLGA/chitosan nanofiber mesh: a platform for wound healing applications.

RSC advances·2025
Same author

Bioinspired Provisional Matrix Stimulates Regenerative Healing of Diabetic Wounds.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society·2025
Same author

Fabrication of cell-laden hydrogel microcapsules of alginate and chitin fibrils using divalent and trivalent metal ions.

RSC advances·2025
Same author

Efficacy and Toxicity Analysis of Selective BET Bromodomain Inhibitors in Models of Inflammatory Liver Disease.

Journal of medicinal chemistry·2025
Same author

Electrospun Polycaprolactone-Gelatin Fibrils Enabled 3D Hydrogel Microcapsules for Biomedical Applications.

Journal of functional biomaterials·2025

Related Experiment Video

Updated: Feb 10, 2026

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications
05:26

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications

Published on: April 13, 2022

4.0K

Magnesium incorporated chitosan based scaffolds for tissue engineering applications.

Udhab Adhikari1,2, Nava P Rijal3,2, Shalil Khanal4,2

  • 1Department of Mechanical Engineering, North Carolina A&T State University, Greensboro, NC, USA.

Bioactive Materials
|May 11, 2018
PubMed
Summary

New bioactive scaffolds from chitosan, carboxymethyl chitosan, and magnesium gluconate show promise for tissue engineering due to their biocompatibility and structural integrity.

Keywords:
Carboxymethyl chitosanChitosanComposite scaffoldsMagnesium gluconateTissue engineering

More Related Videos

Microdissection of Primary Renal Tissue Segments and Incorporation with Novel Scaffold-free Construct Technology
09:00

Microdissection of Primary Renal Tissue Segments and Incorporation with Novel Scaffold-free Construct Technology

Published on: March 27, 2018

8.0K
Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures
05:52

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Published on: September 27, 2019

10.0K

Related Experiment Videos

Last Updated: Feb 10, 2026

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications
05:26

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications

Published on: April 13, 2022

4.0K
Microdissection of Primary Renal Tissue Segments and Incorporation with Novel Scaffold-free Construct Technology
09:00

Microdissection of Primary Renal Tissue Segments and Incorporation with Novel Scaffold-free Construct Technology

Published on: March 27, 2018

8.0K
Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures
05:52

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Published on: September 27, 2019

10.0K

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Biomedical Engineering

Background:

  • Chitosan-based porous scaffolds are valuable in biomedical applications, particularly tissue engineering.
  • Key properties include biocompatibility, controlled degradation, and tunable mechanical characteristics.

Purpose of the Study:

  • To fabricate and characterize novel bioactive scaffolds using chitosan (CS), carboxymethyl chitosan (CMC), and magnesium gluconate (MgG).
  • To evaluate the structural, mechanical, and biological properties of these newly developed scaffolds for tissue engineering suitability.

Main Methods:

  • Scaffolds were prepared via freezing-induced phase separation and lyophilization of polyelectrolyte complexes.
  • Characterization included porosity analysis, mechanical testing (compressive strength, elastic modulus), and in vitro degradation assessment.
  • Cytotoxicity was evaluated using 3T3 fibroblast and osteoblast cell lines.

Main Results:

  • The fabricated scaffolds exhibited uniform porosity with interconnected pores ranging from 50-250 μm.
  • Achieved compressive strengths up to 400 kPa and elastic moduli up to 5 MPa.
  • Scaffolds maintained structural integrity in vitro and showed no cytotoxicity to tested cell lines.

Conclusions:

  • The developed chitosan-based scaffolds demonstrate excellent biocompatibility and mechanical properties.
  • This fabrication method offers a promising approach for creating advanced scaffold materials for tissue engineering applications.
  • The combination of CS, CMC, and MgG yields bioactive scaffolds suitable for regenerative medicine.