Related Experiment Video
Updated: Feb 10, 2026

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility
Published on: September 6, 2024
Biogelx: Cell Culture on Self-Assembling Peptide Gels
Mhairi M Harper1, Michael L Connolly1, Laura Goldie1
1Biogelx Ltd, Biocity Scotland, Lanarkshire, Scotland, UK.
Abstract:
Aromatic peptide amphiphiles can form self-supporting nanostructured hydrogels with tunable mechanical properties and chemical compositions. These hydrogels are increasingly applied in two-dimensional (2D) and three-dimensional (3D) cell culture, where there is a rapidly growing need to store, grow, proliferate, and manipulate naturally derived cells within a hydrated, 3D matrix. Biogelx Limited is a biomaterials company, created to commercialize these bio-inspired hydrogels to cell biologists for a range of cell culture applications. This chapter describes methods of various characterization and cell culture techniques specifically optimized for compatibility with Biogelx products.
Related Concept Videos
Peptide Bonds
Protein Complex Assembly
Many viruses self-assemble into a fully functional unit using the infected host cell to...
Cell Culture
Two-dimensional Gel Electrophoresis
The first dimension separation uses the isoelectric focusing or IEF technique performed on immobilized pH gradient (IPG) strips that separate proteins according to their isoelectric points.
Biological samples, such...
Spindle Assembly
In most cells, centrosomes are the primary microtubule nucleation centers. In the centrosome-mediated pathway, the G2-prophase transition triggers centrosome maturation and increased microtubule nucleation. Progressive nucleation results in a...
Oligosaccharide Assembly
Multiple sugar molecules that may or may...

