[Research progress on the technique and materials for three-dimensional bio-printing].

Area of Science:

• Biomedical Engineering
• Tissue Engineering
• Regenerative Medicine

Context:

• Three-dimensional (3D) bio-printing is an emerging technology for fabricating complex biological constructs.
• It requires careful consideration of biocompatible environments, printing methods, and materials.
• Current research predominantly remains in the experimental phase.

Purpose:

• To review the current research state of 3D bio-printing.
• To emphasize and compare various bio-printing techniques (inkjet, extrusion, stereolithography, laser-assisted).
• To review and compare common bio-printing materials based on cross-linking, biocompatibility, and applications.

Summary:

• This paper details current 3D bio-printing techniques, including inkjet, extrusion, stereolithography, and laser-assisted methods, comparing their precision, processes, requirements, and impact on cell viability.
• It also reviews common bio-printing materials, evaluating their cross-linking properties, biocompatibility, and potential applications.
• The study consolidates existing knowledge to bridge the gap between experimental research and practical implementation.

Impact:

• Provides a comprehensive overview of 3D bio-printing technologies and materials.
• Aims to facilitate the improvement of 3D bio-printing for practical use.
• Contributes to the foundational knowledge for future advancements in the field of bio-fabrication.