Related Experiment Video
Updated: Feb 10, 2026
07:04
A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
Published on: October 24, 2017
8.9K
IL-10 and pregnancy complications.
Clinical and Experimental Obstetrics & Gynecology
|May 11, 2018
Summary
Interleukin 10 (IL-10) is crucial for a healthy pregnancy. This study found significantly lower IL-10 levels in women experiencing pregnancy complications compared to those with normal pregnancies.
Area of Science:
- Immunology
- Reproductive Medicine
- Maternal-Fetal Medicine
Background:
- Successful pregnancy relies on maternal immune tolerance and a supportive environment.
- Interleukin 10 (IL-10) is recognized as vital for normal gestation.
- Reduced IL-10 levels are linked to various pregnancy complications.
Purpose of the Study:
- To compare IL-10 levels in normal versus complicated pregnancies.
- To investigate the role of IL-10 in maintaining a healthy pregnancy.
- To identify potential biomarkers for pregnancy pathologies.
Main Methods:
- Maternal peripheral blood mononuclear cells (PBMC) were collected from women across gestation.
- IL-10 production was measured in women with normal pregnancies and those with complications.
- Complicated pregnancies included recurrent spontaneous miscarriage, preterm delivery, premature rupture of membranes, pre-eclampsia, and intrauterine growth retardation.
Main Results:
- Median IL-10 levels were statistically significantly lower in pathological pregnancy conditions.
- A clear distinction in IL-10 production was observed between normal and complicated gestations.
- Lower IL-10 is associated with adverse pregnancy outcomes.
Conclusions:
- Higher IL-10 levels are indicative of a healthy pregnancy.
- Lower IL-10 levels are associated with pathological pregnancy states.
- IL-10 may serve as a critical factor in pregnancy success and a potential indicator of complications.
Related Concept Videos
01:24Hemodialysis II: Procedure and Complications
937
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
937
01:30Pneumonia III: Complications and Assessment
905
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
905
01:15Diabetes: Symptoms, Diagnosis, and Complications
2.4K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.4K
01:24Asthma-III: Symptoms and Complications
3.4K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
3.4K
01:25Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
870
Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
870
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
3.9K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
3.9K