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Relative Activity Factor (RAF)-Based Scaling of Uptake Clearance Mediated by Organic Anion Transporting Polypeptide

Saki Izumi1, Yoshitane Nozaki1, Hiroyuki Kusuhara2

  • 1Drug Metabolism and Pharmacokinetics Tsukuba , Tsukuba Research Laboratories, Eisai Co., Ltd. , 5-1-3 Tokodai , Tsukuba-shi , Ibaraki 300-2635 , Japan.

Molecular Pharmaceutics
|May 11, 2018
PubMed

Keywords:
hepatic uptakehuman hepatocytesorganic anion transporting polypeptide (OATP)relative activity factor (RAF)

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