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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Prevention of Infectious Complications in Patients With Chronic Granulomatous Disease
Maria A Slack1, Isaac P Thomsen2
1Division of Allergy and Immunology, Department of Pediatrics, University of Rochester Medical Center and Golisano Children's Hospital, New York.
Abstract:
Chronic granulomatous disease (CGD) is a primary immunodeficiency that confers a markedly increased risk of bacterial and fungal infections caused by certain opportunistic pathogens. Current evidence supports the use of prophylactic antibacterial, antifungal, and immunomodulatory therapies designed to prevent serious or life-threatening infections in patients with CGD. In this review, we discuss current strategies for the prevention of infections in children and adults with CGD and the evidence that supports those strategies. In addition, we address current challenges and opportunities for future research in this important area.
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