Ventricular aberrant bands and hypertrophic trabeculations. A clinical pathological correlation

Area of Science:

• Cardiovascular Pathology
• Cardiac Surgery

Background:

• Aberrant bands and hypertrophic trabeculations are observed in cardiac pathology.
• Their precise definition and prevalence in different heart conditions require further elucidation.

Purpose of the Study:

• To pathologically define left ventricular (LV) and right ventricular (RV) aberrant bands and hypertrophic trabeculations.
• To compare their prevalence and characteristics in dilated congestive cardiomyopathy versus ischemic heart disease.

Main Methods:

• Review of clinical, hemodynamic, and pathology data from 22 dilated congestive cardiomyopathy and 13 ischemic heart disease patients undergoing heart transplantation.
• Morphological and histological analysis of aberrant bands and trabeculations.

Main Results:

• Prevalence of LV aberrant bands was 37% and RV was 28%.
• Prevalence of LV hypertrophic trabeculations was 43% and RV was 28%.
• Dilated cardiomyopathy patients had higher prevalence of LV aberrant bands and hypertrophic trabeculations compared to ischemic heart disease patients.
• Aberrant bands associated with dilated cavities; hypertrophic trabeculations with ventricular hypertrophy and smaller LV size.
• Proposed classification of aberrant bands into genuine (congenital) and secondary (pathology-induced) types.

Conclusions:

• Aberrant bands and hypertrophic trabeculations exhibit distinct morphological features and associations with cardiac conditions.
• Distinguishing between genuine and secondary bands is crucial for understanding their origin and implications.
• These findings contribute to the pathological definition of ventricular anomalies.