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Metabolic acidosis as Food Protein Induced Enterocolitis Syndrome (FPIES) onset in a newborn

Antonella Peduto1, Mario Rocca2, Cinzia De Maio3

  • 1Pediatric Unit, S. Croce Hospital, Cuneo, Italy. peduto.a@ospedale.cuneo.it.

Italian Journal of Pediatrics
|May 12, 2018
PubMed

Insights

Food Protein Induced Enterolitis Syndrome (FPIES) is a rare food allergy. Early recognition is key for managing FPIES in infants presenting with metabolic acidosis.

Area of Science:

  • Pediatric Gastroenterology
  • Allergy Immunology

Background:

  • Food Protein Induced Enterolitis Syndrome (FPIES) is a non-IgE mediated food allergy affecting infants.
  • It presents with diverse symptoms including vomiting, diarrhea, and failure to thrive.

Observation:

  • A 12-day-old infant presented with poor feeding, failure to thrive, and severe metabolic acidosis.
  • This early onset is unusual for typical FPIES presentations.

Findings:

  • The case highlights FPIES as a potential cause of metabolic acidosis in newborns.
  • Diagnosis relies on clinical criteria after excluding other conditions.

Implications:

  • Consider FPIES in the differential diagnosis of neonatal metabolic acidosis.
  • Early identification enables timely dietary management and resolution of FPIES symptoms.
Abstract

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