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Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging
Published on: May 24, 2021
Imaging Right-Left Ventricular Interactions
1Labatt Family Heart Center, The Hospital for Sick Children, and Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada.
Insights
Understanding how one ventricle affects the other is crucial for heart function. Echocardiography imaging helps assess these ventricular-ventricular interactions in various heart conditions, with advanced techniques improving insights.
Area of Science:
- Cardiology
- Medical Imaging
- Physiology
Background:
- Ventricular-ventricular interactions are fundamental to overall cardiac function.
- These interactions are influenced by anatomical structures like the interventricular septum and myocardial tracts.
- Understanding these dynamics is vital in both acquired and congenital heart diseases.
Purpose of the Study:
- To review the role of cardiac imaging, particularly echocardiography, in assessing ventricular-ventricular interactions.
- To highlight how advanced imaging techniques can enhance the understanding of these interactions.
- To emphasize the importance of analyzing imaging findings within the context of pathophysiology.
Main Methods:
- Characterization of ventricular-ventricular interactions using echocardiography.
- Assessment of geometric indices, septal motion, Doppler flow, and ventricular timing.
- Evaluation of strain, remodeling, and diastolic filling patterns, considering contralateral ventricular loading.
Main Results:
- Standard echocardiography is often adequate for imaging ventricular-ventricular interactions.
- Advanced techniques like 3D echocardiography and automated post-processing show promise for improved detection.
- Imaging findings, when correlated with pathophysiology, are essential for accurate assessment.
Conclusions:
- Echocardiography is a cornerstone for evaluating ventricular-ventricular interactions.
- Technological advancements are refining the ability to detect and understand these crucial cardiac dynamics.
- Comprehensive analysis of imaging data is key to managing diverse cardiac conditions.
Abstract:
The impact of one ventricle on the adjacent ventricle plays a key role in cardiac function. Ventricular-ventricular interactions are based on the arrangement in-series of the circulation and common pericardium, interventricular septum, and myocardial tracts. Imaging, in particular echocardiography, plays a central role in characterizing these interactions through geometric indices, septal configuration and motion, Doppler flow, timing of events in the ventricles and alterations in strain, remodeling, and diastolic filling with altered loading of the contralateral ventricle. Although standard echocardiography techniques are usually adequate to image ventricular-ventricular interactions, recent developments in automation, post-processing, and advanced techniques (e.g., 3-dimensional) could improve detection and understanding of interventricular interactions. Imaging findings must be analyzed in the context of the pathophysiology to correctly assess and understand ventricular-ventricular interactions. This paper reviews the imaging of ventricular-ventricular interactions in acquired and congenital heart disease, demonstrating their importance in a wide array of conditions.
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