Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interoceptive processing deficit: A behavioral marker for subtyping Parkinson's disease.

Gabriella Santangelo1, Carmine Vitale2, Chiara Baiano1

  • 1Department of Psychology, University of Campania Luigi Vanvitelli, Caserta, Italy.

Parkinsonism & Related Disorders
|May 12, 2018
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Device aided therapies in Parkinson disease: an expert view on apomorphine.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same author

Psychosocial and body image alterations associated with focal dystonia.

Journal of neural transmission (Vienna, Austria : 1996)·2026
Same author

Exploring the relationship between interoception and mental body representation in Parkinson's disease.

Journal of neural transmission (Vienna, Austria : 1996)·2026
Same author

Social cognition in idiopathic focal dystonia: preliminary evidence on its relationship with cognitive and affective-behavioral functioning.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same author

Refining neuropsychological assessment strategies in multiple sclerosis: insights from long-term cognitive trajectories.

Journal of neurology·2026
Same author

Immersive Virtual Reality in Neuropsychological Assessment of Acquired Brain Injury: a Systematic Review and Meta-Analysis.

Neuropsychology review·2026

Tremor-dominant Parkinson's disease (PD) patients exhibit impaired interoception, affecting their ability to sense internal body states. This finding suggests interoceptive processing deficits can help differentiate PD subtypes.

Area of Science:

  • Neuroscience
  • Clinical Neurology
  • Psychology

Background:

  • Parkinson's disease (PD) presents with non-motor symptoms that vary between tremor-dominant (TD) and postural instability/gait difficulty (PIGD) subtypes.
  • Non-motor symptoms like anxiety and depression are linked to interoception, the sense of the body's internal state.
  • Previous research indicates potential interoceptive deficits in Parkinson's disease.

Purpose of the Study:

  • To investigate if interoceptive processing differs between TD and PIGD subtypes of Parkinson's disease.
  • To assess interoceptive accuracy and sensibility in PD subtypes and healthy controls.

Main Methods:

  • Interoceptive accuracy was measured using a heartbeat perception task.
  • Interoceptive sensibility was evaluated via a subjective interoception questionnaire.
Keywords:
CerebellumInteroceptionParkinson's diseasePostural instability/gait difficulty phenotypeTremor dominant phenotype

Related Experiment Videos

  • Patients also completed assessments for anxiety, depression, apathy, anhedonia, and impulsive-compulsive behaviors.

    • Main Results:

    • Patients with the TD subtype of Parkinson's disease showed reduced interoceptive accuracy and sensibility compared to PIGD patients and controls.
    • The TD group's deficits in interoceptive accuracy were specific, as their performance on a control time-estimation task was similar to other groups.

    Conclusions:

    • Interoceptive processing deficits are more pronounced in the tremor-dominant subtype of Parkinson's disease.
    • Behavioral assessment of interoception can serve as a valuable marker for subtyping Parkinson's disease patients.