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Infant-juvenile type 2 diabetes
M L Calero Bernal1, J M Varela Aguilar2
1Servicio de Medicina Interna, Hospital San Juan de Dios del Aljarafe, Bormujos, Sevilla, España; Grupo de trabajo de Diabetes y Obesidad de SEMI, España.
Insights
Childhood type 2 diabetes mellitus (DM2) is rising with obesity. Early detection and management in at-risk youth are crucial to prevent long-term complications, as pediatric DM2 requires lifelong care.
Area of Science:
- Pediatrics
- Endocrinology
- Public Health
Background:
- Increasing prevalence of childhood obesity worldwide.
- Parallel rise in type 2 diabetes mellitus (DM2) cases among children and adolescents.
- Insulin resistance as a key factor in pediatric DM2 development.
Purpose of the Study:
- To highlight the growing concern of type 2 diabetes mellitus in pediatric populations.
- To emphasize the need for targeted screening in at-risk children.
- To underscore the importance of managing comorbidities and long-term complications.
Main Methods:
- Review of recent trends in childhood type 2 diabetes mellitus.
- Analysis of the link between obesity and insulin resistance in youth.
- Assessment of comorbidities associated with pediatric DM2 diagnosis.
Main Results:
- Significant increase in type 2 diabetes mellitus cases in children and adolescents.
- Obesity identified as a primary risk factor for pediatric DM2.
- Comorbidities like hypertension and dyslipidemia are common in diagnosed children.
Conclusions:
- Targeted screening for type 2 diabetes mellitus in overweight or obese children is recommended.
- Comprehensive assessment and management of comorbidities are essential for preventing long-term complications.
- Pediatric-onset type 2 diabetes mellitus necessitates lifelong management due to its prolonged duration.
Abstract:
In recent years, we have witnessed an increase in the number of cases of type 2 diabetes mellitus (DM2) in children and adolescents, which has paralleled the increase in the worldwide prevalence of obesity. Although screening the general population does not appear to be cost-effective, special attention should be paid to children with excess weight, obesity or other factors that predispose them to a state of insulin resistance. When faced with the diagnosis of childhood DM2, the presence of comorbidities (such as hypertension, dyslipidemia and microalbuminuria) should be assessed, and appropriate treatment and follow-up should be administered to prevent the onset of complications, given that the DM2 in this population group will last longer than that started in adulthood.
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