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The China Patient-centered Evaluative Assessment of Cardiac Events (China PEACE) retrospective heart failure study
Yuan Yu1,2, Hongzhao Zhang1, Xi Li1
1National Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Fuwai Hospital, Beijing, China.
Insights
This study outlines the methodology for the China Patient-centered Evaluative Assessment of Cardiac Events 5 Retrospective Heart Failure Study (China PEACE 5r-HF). It aims to understand heart failure (HF) burden, care quality, and outcomes in China.
Area of Science:
- Cardiology
- Public Health
- Health Services Research
Background:
- Heart failure (HF) is a major cause of hospitalization in China, with rising cardiovascular disease prevalence.
- There is limited understanding of the current burden, quality of care, and treatment outcomes for HF in China.
Purpose of the Study:
- To describe the study methodology, data collection, and progress of the China Patient-centered Evaluative Assessment of Cardiac Events 5 Retrospective Heart Failure Study (China PEACE 5r-HF).
- To establish a foundation for improving HF care in China.
Main Methods:
- Retrospective cohort study examining over 10,000 patient records hospitalized for HF in China in 2015.
- Two-stage sampling design stratified by economic-geographical regions.
- Collection of patient characteristics, diagnostics, treatments, in-hospital outcomes (including mortality and complications), and hospitalization charges.
Main Results:
- As of October 2017, 15,538 medical records were sampled from 189 hospitals.
- Data collection was completed for 15,057 records (96.9%), with abstraction and quality control finished for 7,971.
Conclusions:
- The China PEACE 5r-HF study is progressing to provide critical insights into heart failure management in China.
- Findings will be disseminated to inform future improvements in HF care nationwide.
Introduction:
Heart failure (HF) is a leading cause of hospitalisation in China, which is experiencing a rapid increase in cardiovascular disease prevalence. Yet, little is known about current burden of disease, quality of care and treatment outcomes of HF in China. The objective of this paper is to describe the study methodology, data collection and abstraction, and progress to date of the China Patient-centered Evaluative Assessment of Cardiac Events 5 Retrospective Heart Failure Study (China PEACE 5r-HF).
Methods And Analysis:
The China PEACE 5r-HF Study will examine a nationally representative sample of more than 10 000 patient records hospitalised for HF in 2015 in China. The study is a retrospective cohort study. Patients have been selected using a two-stage sampling design stratified by economic-geographical regions. We will collect patient characteristics, diagnostic testing, treatments and in-hospital outcomes, including death and complications, and charges of hospitalisation. Data quality will be monitored by a central coordinating centre and will address case ascertainment, data abstraction and data management. As of October 2017, we have sampled 15 538 medical records from 189 hospitals, and have received 15 057 (96.9%) of these for data collection, and completed data abstraction and quality control on 7971.
Ethics And Dissemination:
The Central Ethics Committee at the Chinese National Center for Cardiovascular Diseases approved the study. All collaborating hospitals accepted central ethics committee approval with the exception of 15 hospitals, which obtained local approval by internal ethics committees. Findings will be disseminated in future peer-reviewed papers and will serve as a foundation for improving the care for HF in China.
Trial Registration Number:
NCT02877914.
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