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Suppression of conditioned avoidance by 8-OH-DPAT in the rat
1Department of Psychology, University of Stockholm, Sweden.
Journal of Neural Transmission
|January 1, 1988
Abstract:
Rats were trained to perform an aversely motivated discriminative task in a shuttle-box. The conditioned avoidance response was selectively suppressed by 8-OH-DPAT in a dose-dependent manner (25-100 micrograms.kg-1). There were no statistically significant deficits in discriminative performance. The present results suggest antipsychotic-like properties of 8-OH-DPAT.