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Updated: Feb 10, 2026

A Simple Flow Cytometric Method to Measure Glucose Uptake and Glucose Transporter Expression for Monocyte Subpopulations in Whole Blood
Published on: August 12, 2016
Recent progress of sodium-glucose transporter 2 inhibitors as potential antidiabetic agents
Yajing Zhang1, Huazhuo Ban1, Runan Yu1
1Center of Drug Discovery, Institute of Pharmaceutical Sciences, China Pharmaceutical University, Nanjing 210009, PR China.
Abstract:
SGLT2 inhibitors were promising and novel antidiabetic drugs which suppressed glucose reabsorption and increased urinary glucose exertion. This review paper are aimed to summarize the recent progress of SGLT2 inhibitors during the last 5 years. This paper first summarizes the information of SGLT2 inhibitors, including mechanism, evolution and then focuses on the recent efforts on structure-activity relationships and structural optimization of SGLT2 inhibitors. Finally, the corresponding clinical therapeutic efficacy and adverse drug reaction in patients with Type 2 diabetes are discussed in detail.
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