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Updated: Feb 10, 2026
10:40
Visualization and Analysis of Blood Flow and Oxygen Consumption in Hepatic Microcirculation: Application to an Acute Hepatitis Model
Published on: August 4, 2012
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Acute Viral Hepatitis: Beyond A, B, and C
Venancio Avancini Ferreira Alves1
1Department of Pathology, Surgical Pathology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil.
Surgical Pathology Clinics
|May 13, 2018
Summary
This article details the histologic patterns of liver injury in acute viral hepatitis caused by various viruses, including hepatotropic and other systemic infections. It focuses on the pathologist's perspective of hepatitis, covering causes like autoimmune disease and toxins.
Area of Science:
- Hepatology
- Surgical Pathology
- Virology
Background:
- Hepatitis is histologically defined by patterns of liver lesions.
- Causes include viral infections, autoimmune diseases, drugs, and toxins.
Purpose of the Study:
- To describe the histologic patterns of injury in acute viral hepatitis.
- To cover hepatotropic viruses (A, B, C, D, E) and related hemorrhagic fevers.
- To briefly mention hepatitis in immunosuppressed patients.
Main Methods:
- Histologic examination of liver biopsies.
- Review of literature on viral hepatitis and liver injury patterns.
Main Results:
- Detailed description of characteristic histologic findings for each viral hepatitis type.
- Identification of shared and distinct patterns of hepatocellular injury.
- Correlation of histologic patterns with specific viral agents.
Conclusions:
- Histologic patterns are crucial for diagnosing and understanding the pathogenesis of acute viral hepatitis.
- Recognizing specific patterns aids in differentiating viral etiologies and other causes of liver inflammation.
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