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Updated: Feb 10, 2026

Microscopic Replantation of Penile Glans Amputation Due to Circumcision
Published on: June 3, 2022
Immediate Versus Overnight-Delayed Digital Replantation: Comparative Retrospective Cohort Study of Survival Outcomes
Pedro C Cavadas1, Carlos Rubí2, Alessandro Thione1
1Reconstructive Surgery Unit, Clínica Cavadas, Valencia, Spain.
Purpose:
Ischemia time has been traditionally considered a critical factor in replantation survival rate. The objective of this study was to compare the survival rate between immediate and overnight-delayed digital replantation.
Methods:
We performed a retrospective cohort study of all digital replantations performed at our clinic between 2005 and 2016. The survival rate was compared between the immediate digital replantation group (immediate replantation group) and those that were replanted the morning after they were admitted to the hospital (overnight-delayed replantation group). The decision to delay the replant was made in cases admitted in the evening with less than 12 hours of previous ischemia time and without farm-related contamination.
Results:
Five hundred ninety-seven digital replantations (456 patients) were analyzed. One hundred eighty-five (31%) digital replantations were performed the following day (delayed replantation group) and 412 (69%) digital replantations were performed the same day that they were admitted to the hospital (immediate replantation group). The overall survival rate was 91.9% (549 of 597). In the immediate replantation group, the survival rate was 91.2% (376 of 412) and in the delayed replantation group, the survival rate was 93.4% (174 of 185). There were no statistically significant differences between the immediate and the delayed replantation groups with respect to age, zone of amputation, or presence of multiple amputations.
Conclusions:
Our study suggests that overnight delay is a safe approach for digital replantation when performed by experienced microsurgeons.
Type Of Study/Level Of Evidence:
Prognostic IV.
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