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Chronic Kidney Disease in Persons Living with HIV: A Systematic Review

Jungmin Park, Julie Ann Zuñiga

    The Journal of the Association of Nurses in AIDS Care : JANAC
    |May 13, 2018
    PubMed

    Insights

    Chronic kidney disease (CKD) affects persons living with HIV (PLWH), with risk factors including hypertension, diabetes, and age. Prevalence varies widely among PLWH populations globally.

    Area of Science:

    • Nephrology
    • Infectious Diseases
    • Public Health

    Background:

    • Chronic kidney disease (CKD) is a significant concern in persons living with HIV (PLWH).
    • Understanding CKD's prevalence, risk factors, and diagnostic criteria in PLWH is crucial for effective management.

    Purpose of the Study:

    • To systematically review research on CKD in PLWH.
    • Compare diagnostic criteria for CKD in PLWH.
    • Identify key risk factors for CKD development in PLWH.
    • Determine the prevalence of CKD among PLWH populations.

    Main Methods:

    • Systematic review of studies published between 2000 and 2016.
    • Searches conducted in PubMed and PsycInfo databases, supplemented by manual reference checks.
    • Inclusion of 21 studies with diverse sample sizes, age groups, ethnicities, and geographical origins.

    Main Results:

    • Major identified risk factors for CKD in PLWH include hypertension, diabetes, and advanced age.
    • Prevalence of CKD in PLWH varied significantly, ranging from 2.3% to 53.3%.
    • Disparities in prevalence may be attributed to differences in risk factor profiles across studied populations.

    Conclusions:

    • Hypertension, diabetes, and age are critical risk factors for CKD in PLWH.
    • The wide range in CKD prevalence highlights the need for population-specific risk assessments.
    • Further research is warranted to refine diagnostic criteria and management strategies for CKD in PLWH.

    Keywords:
    HIVchronic kidney diseasecomorbid conditionssystematic review

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