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High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
Published on: May 10, 2016
[Links between self-harm and suicidal behaviour in adolescents]
Salomé Grandclerc1, Jonathan Lachal1
1Université Paris Descartes, faculté de médecine, Sorbonne Paris-Cité, 15, rue de l'École-de-médecine, 75006 Paris, France; Maison de Solenn-MDA, hôpital Cochin, 97, boulevard Port-Royal, 75014 Paris, France; CESP, faculté de médecine, université Paris-Sud, faculté de médecine-UVSQ, Inserm, Université Paris-Saclay, 16, avenue Paul-Vaillant-Couturier, 94805 Villejuif, France.
Nonsuicidal self-injury (NSSI) and suicidal behavior (SB) in adolescents share risk factors and may be linked. NSSI might enable suicidal capability by bypassing cognitive processes, making intent assessment challenging.
Area of Science:
- Adolescent health
- Mental health
- Psychiatry
Background:
- Nonsuicidal self-injury (NSSI) and suicidal behavior (SB) are significant concerns in adolescent healthcare.
- These behaviors frequently co-occur, necessitating an understanding of their relationship.
- Shared risk factors link NSSI and SB, highlighting common underlying vulnerabilities.
Purpose of the Study:
- To explore the intricate relationship between NSSI and SB in adolescents.
- To examine how NSSI may influence the development of suicidal capability.
- To address the challenges in assessing suicidal intent within the context of NSSI.
Main Methods:
- This study reviews existing literature and theoretical models on NSSI and SB.
- It analyzes the shared risk factors contributing to both behaviors.
- The research examines integrated models proposing NSSI as a pathway to suicidal capability.
Main Results:
- NSSI and SB share common risk factors, indicating overlapping etiological pathways.
- Integrated models suggest NSSI can facilitate the acquisition of suicidal capability in adolescents.
- Assessing the underlying suicidal intent in NSSI acts is complex and challenging.
Conclusions:
- Understanding the link between NSSI and SB is crucial for effective adolescent mental healthcare.
- NSSI may serve as a critical juncture, potentially increasing an adolescent's capacity for suicide.
- Further research is needed to improve the assessment of suicidal intent in adolescents exhibiting NSSI.
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