Related Experiment Video
Updated: Feb 10, 2026

Computerized Adaptive Testing System of Functional Assessment of Stroke
Published on: January 7, 2019
Assessment of esophageal function using provocative tests during high resolution manometry: A single-center
Ming-Wun Wong1, Wei-Yi Lei2, Jui-Sheng Hung3
1Department of Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan; PhD Program in Pharmacology and Toxicology, Tzu Chi University, Hualien, Taiwan.
Background:
Provocative tests were used to provide additional information during performing high resolution manometry (HRM). The study aimed to evaluate whether it is feasible to test esophageal function with different esophageal provocative tests during HRM.
Methods:
23 healthy volunteers (9 women; mean age 25 years, range 21-30 years) underwent water-perfused HRM. Each subject received 10 liquid swallows, 10 solid swallows, 10 liquid swallows with abdominal compression, and 5 multiple rapid swallowing (MRS).
Results:
DCI was significantly greater during abdominal compression than that of solid swallows (p = 0.025). Compared with liquid swallows, there was a significant decrease in CFV during solid swallows (p = 0.04). DL was significantly greater during solid swallows than that of liquid swallows (p < 0.001) or abdominal compression (p < 0.001). IRP 4s was significantly lower during abdominal compression than that of liquids (p < 0.001) or solid swallows (p = 0.006). All subjects had complete inhibition during MRS and increased DCI after MRS as compared with liquid swallows (p < 0.05).
Conclusion:
Esophageal provocative test may provide additional utility in performing HRM studies. The data for esophageal provocative tests are distinct from standard liquid swallows.
Related Concept Videos
Pulmonary Function Tests
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Lattice Centering and Coordination Number
Types of Unit Cells
Imagine taking a large number of identical...
Serum Studies: Renal Function Tests
Esophageal Varices-I: Introduction
Center of Gravity
Center of Gravity
To determine its location, the principle of moments can be utilized by dividing the object into...

