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Data Reporting and Recording01:24

Data Reporting and Recording

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Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
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Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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Giant dentinogenic ghost cell tumor: A case report.

Ciro Dantas Soares1, Roman Carlos2, Thayná Melo de Lima Morais1

  • 1Oral Pathology Section, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.

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This summary is machine-generated.

Dentinogenic ghost cell tumors (DGCT) are rare but aggressive odontogenic tumors. This report details the largest case of DGCT, emphasizing its unique presentation and successful surgical management.

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Area of Science:

  • Oral Pathology
  • Oncology
  • Surgical Dentistry

Background:

  • Dentinogenic ghost cell tumor (DGCT) is a rare odontogenic neoplasm.
  • Characterized by aggressive local behavior, bone destruction, and cortical expansion.

Observation:

  • A 38-year-old male presented with a large DGCT causing significant extraoral protrusion.
  • Radiographic analysis showed a mixed radiolucent-radiopaque lesion.
  • Histopathology revealed ameloblastomatous proliferation with ghost cells, dentinoid material, and pseudoglandular structures.

Findings:

  • Immunohistochemistry confirmed DGCT with positive staining for pan-cytokeratin (CK), CK-14, CK-7, CK-19, CD138, and β-catenin.
  • A very low Ki-67 proliferative index (<1%) was noted.
  • The largest DGCT case reported in English literature.

Implications:

  • Accurate diagnosis relies on integrating clinical, histopathologic, and immunohistochemical findings.
  • Surgical resection, such as partial mandibulectomy, can achieve successful outcomes.
  • This case expands the understanding of DGCT size and presentation.