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Updated: Feb 10, 2026

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
Published on: September 10, 2013
A multifunctional fluorescence sensor for Cd2+, PO43- and Cr3+ in different system and the practical application
Qingming Wang1, Yingzi Tan2, Nianhua Wang2
1School of Pharmacy, Jiangsu Provincial Key Laboratory of Coastal Wetland Bioresources and Environmental Protection, Yancheng Teachers' University, Yancheng, Jiangsu 224051, People's Republic of China; State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing 210093, People's Republic of China.
Abstract:
A fluorescence probe based on thiosemicarbazide has been synthesized and well characterized by 1H NMR, 13C NMR, Elemental analysis, Electrospray ionization mass spectra. The probe 1 functions as a multitarget ion sensor, detect biologically and ecologically important Cd2+, PO43- and Cr3+. Meanwhile, probe 1 displays selectivity for Cd2+ over other metal ions and anions in DMF by emission spectrum. Interestingly, probe 1 has been explored to recognize PO43- in CH3OH-H2O (v:v = 1:9). The binding stoichiometry of probe 1 with Cd2+ and PO43- are 2:1 and 1:1, respectively, which are confirmed by Electrospray ionization mass spectra. Probe 1 is selective, sensitive and reversibility/reusability to Cd2+ and PO43- with the detection limit as low as 0.035 μM and 0.011 μM respectively. Besides, the designed probe 1 has shown potential applications in the area of photo-printing.
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