Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Patch Clamp01:18

Patch Clamp

6.6K
Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
6.6K
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

421
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
421
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

692
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
692
Regulation of Stroke Volume01:27

Regulation of Stroke Volume

5.2K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
5.2K
Persuasion Strategies01:52

Persuasion Strategies

43.5K
Researchers have tested many persuasion strategies, including the foot-in-the door and the door-in-the-face techniques, in a variety of contexts. Ultimately, the principles are effective in selling products and changing people’s attitude, ideas, and behaviors (Cialdini & Goldstein, 2004).
43.5K
Coping Strategies: Problem Focused01:27

Coping Strategies: Problem Focused

529
Coping strategies are methods people use to manage, tolerate, or reduce the effects of stressors. These strategies involve both behavioral and psychological actions to handle stressful situations. One common approach is problem-focused coping, which aims to change or eliminate the source of stress rather than merely addressing its consequences. This method involves taking direct action to resolve the issue causing stress.
For example, consider a student who struggles to understand their...
529

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-term outcomes of postoperative atrial fibrillation after cardiac surgery: Results from 19,000 patients.

The Journal of thoracic and cardiovascular surgery·2026
Same author

Impact of Circulatory Arrest Duration on Perioperative Mortality: Insights From More Than 1200 Aortic Arch Reconstructions.

The Annals of thoracic surgery·2026
Same author

Exploratory Laparotomy After Routine Cardiac Surgery: Results From 17,000 Patients.

World journal of surgery·2026
Same author

Sodium-glucose cotransporter 2 inhibitor use and outcomes after surgical aortic valve replacement.

The Journal of thoracic and cardiovascular surgery·2026
Same author

Association of GLP-1 inhibitors with cardiovascular outcomes in patients undergoing coronary artery bypass surgery.

The Journal of thoracic and cardiovascular surgery·2026
Same author

Missing the Act on the Mission of Maintaining Quality Care.

JAMA surgery·2026

Related Experiment Video

Updated: Feb 10, 2026

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats
06:50

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats

Published on: August 15, 2025

431

Aortic clamping strategy and postoperative stroke.

Mohamad Alaeddine1, Vinay Badhwar2, Maria V Grau-Sepulveda3

  • 1Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pa.

The Journal of Thoracic and Cardiovascular Surgery
|May 15, 2018
PubMed
Summary

Partial occluding clamp (POC) technique for coronary artery bypass grafting (CABG) does not increase stroke risk compared to single clamp (SC). POC use resulted in shorter ischemic and bypass times, demonstrating comparable safety and improved efficiency in CABG procedures.

Keywords:
CABGdatabasestroke

More Related Videos

Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model
08:33

Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model

Published on: November 24, 2016

9.8K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.9K

Related Experiment Videos

Last Updated: Feb 10, 2026

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats
06:50

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats

Published on: August 15, 2025

431
Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model
08:33

Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model

Published on: November 24, 2016

9.8K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.9K

Area of Science:

  • Cardiovascular Surgery
  • Surgical Techniques
  • Patient Outcomes

Background:

  • Coronary artery bypass grafting (CABG) involves aortic clamping, with varying strategies potentially impacting patient outcomes.
  • The effect of different aortic clamping methods on short-term stroke incidence during proximal graft construction is not well-defined.

Purpose of the Study:

  • To evaluate whether the partial occluding clamp (POC) technique increases postoperative stroke incidence compared to the single clamp (SC) technique in CABG.
  • To compare myocardial ischemic times and cardiopulmonary bypass times between POC and SC techniques.

Main Methods:

  • Analysis of 52,611 on-pump CABG patients from the Society of Thoracic Surgeons Adult Cardiac Surgery Database (July 2014 - March 2015).
  • Propensity score matching was used to create 17,819 pairs comparing POC and SC techniques, adjusting for baseline stroke risk.
  • Outcomes analyzed included postoperative stroke rates, mortality rates, myocardial ischemic times, and cardiopulmonary bypass times.

Main Results:

  • Myocardial ischemic times were significantly shorter with POC (57.0 ± 23.3 min) versus SC (74.1 ± 29.2 min).
  • Cardiopulmonary bypass times were also shorter with POC (89.7 ± 34.4 min) versus SC (95.0 ± 35.0 min).
  • Postoperative stroke rates were similar between groups (1.1% for POC vs. 0.9% for SC), as were mortality rates (1.3% for both).

Conclusions:

  • The choice of aortic clamping strategy (POC vs. SC) does not influence short-term postoperative stroke or mortality rates in CABG.
  • The POC technique offers advantages by reducing myocardial ischemic and perfusion times compared to the SC technique.
  • Both clamping strategies demonstrate comparable safety profiles regarding stroke and mortality in CABG procedures.