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Updated: Feb 10, 2026

Hydrolysis of a Ni-Schiff-Base Complex Using Conditions Suitable for Retention of Acid-labile Protecting Groups
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Vitamin D Switches BAF Complexes to Protect β Cells

Zong Wei1, Eiji Yoshihara1, Nanhai He1

  • 1Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

Cell
|May 15, 2018
PubMed
Summary

Vitamin D receptor (VDR) plays a crucial role in protecting pancreatic beta cells from inflammation and dysfunction in type 2 diabetes (T2D). Targeting VDR-chromatin interactions offers a new therapeutic strategy for T2D.

Keywords:
BAF complexBRD9CRISPR screeningPBAF complexVDRchromatin remodelingdiabetesinflammationnuclear receptorβ cell

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