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Updated: Jun 26, 2026

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
Published on: July 11, 2016
Stenotrophomonas maltophilia
1The Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, BT9 7BL, UK.
Abstract:
This infographic describes the key regulated traits of Stenotrophomonas maltophilia, important for beneficial plant interactions, and also its increasing incidence as a nosocomial and community-acquired infection. Stenotrophomonas maltophilia is a cosmopolitan and ubiquitous bacterium found in a range of environmental habitats, including extreme ones, although in nature it is mainly associated with plants. S. maltophilia fulfils important ecosystem functions in the sulfur and nitrogen cycles, in degradation of complex compounds and pollutants, and in promoti on of plant growth and health. Stenotrophomonas can also colonize extreme man-made niches in hospitals, space shuttles, and clean rooms. S. maltophilia has emerged as a global opportunistic human pathogen, which does not usually infect healthy hosts but is associated with high morbidity and mortality in severely immunocompromised and debilitated individuals. S. maltophilia can also be recovered from polymicrobial infections, most notably from the respiratory tract of cystic fibrosis patients. Close relatives of S. maltophilia, for example, S. rhizophila, provide a harmless alternative for biotechnological applications without human health risks.
Insights
Stenotrophomonas maltophilia is a versatile bacterium beneficial to plants but also a growing cause of hospital and community infections. Understanding its traits is crucial for managing its dual role in ecosystems and human health.
Area of Science:
- Microbiology
- Environmental Science
- Infectious Diseases
Background:
- Stenotrophomonas maltophilia is a ubiquitous bacterium found in diverse environments, notably associated with plants.
- It plays significant roles in ecosystem functions like nutrient cycling and plant growth promotion.
- The bacterium is also increasingly recognized as an opportunistic human pathogen.
Purpose of the Study:
- To describe the key regulated traits of Stenotrophomonas maltophilia.
- To highlight its importance in plant interactions.
- To address its rising incidence as a nosocomial and community-acquired infection.
Main Methods:
- Infographic description of regulated traits.
- Review of environmental and clinical incidence data.
- Comparison with harmless relatives like S. rhizophila.
Main Results:
- S. maltophilia exhibits traits beneficial for plant growth and ecosystem functions.
- It colonizes various habitats, including extreme environments and man-made niches like hospitals.
- The pathogen causes significant morbidity and mortality in immunocompromised individuals and in polymicrobial infections.
Conclusions:
- Stenotrophomonas maltophilia possesses a dual nature, being ecologically important and a significant human pathogen.
- Its increasing incidence necessitates further research and understanding.
- Harmless relatives offer safer alternatives for biotechnological applications.
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