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Peak vertical force in a stabilized canine cranial cruciate deficient stifle model: A one-year follow-up
Bertrand Lussier1, Alexandre Gagnon1, Maxim Moreau1
1Quebec Animal Pharmacology Research Group (Groupe de recherche en pharmacologie animale du Québec; GREPAQ), Université de Montréal, Saint-Hyacinthe, Quebec J2S 2M2 (Lussier, Gagnon, Moreau, Troncy); Osteoarthritis Research Unit, Centre hospitalier de l'Université de Montréal, Hôpital Notre-Dame, Montreal, Quebec H2L 4M1 (Lussier, Moreau, Pelletier, Troncy).
Abstract:
This study aimed to describe the peak vertical force (PVF) over a 1-year period in a stabilized canine cranial cruciate deficient stifle model. Our hypothesis was that PVF would be restored to Baseline (intact) at the end of the follow-up. Fifteen (> 20 kg) mixed-breed dogs were included in this study. Cranial cruciate ligament was transected on Day (D) 0 followed by lateral suture stabilization at D28. Peak vertical force was acquired at D-1, D14, D26, D91, D210 and D357. When compared to Baseline, the PVF was significantly decreased at D14, D26, and D91. Values at D210 and D357 were not statistically different to Baseline. This study suggests a return to normal baseline peak vertical force in a canine cranial cruciate deficient stifle model when lateral suture stabilization has been performed 28 days after surgical transection.
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